Background: The population ageing in most Western countries leads to a larger number of frail older people. These frail people are at an increased risk of negative health outcomes, such as functional decline, falls, institutionalisation and mortality. Many approaches are available for identifying frailty among older people. Researchers most often use Fried and colleagues’ description of the frailty phenotype. The authors describe five physical criteria. Other researchers prefer a combination of measurements in the social, psychological and/or physical domains. The aim of this study is to describe the levels of social, psychological and physical functioning according to Fried’s frailty stages using a large cohort of Dutch community-dwelling older people. Methods: There were 8,684 community-dwelling older people (65+) who participated in this cross-sectional study. Based on the five Fried frailty criteria (weight loss, exhaustion, low physical activity, slowness, weakness), the participants were divided into three stages: non-frail (score 0), pre-frail (score 1–2) and frail (score 3–5). These stages were related to scores in the social (social network type, informal care use, loneliness), psychological (psychological distress, mastery, self-management) and physical (chronic diseases, GARS IADL-disability, OECD disability) domains. Results: 63.2 % of the participants was non-frail, 28.1 % pre-frail and 8.7 % frail. When comparing the three stages of frailty, frail people appeared to be older, were more likely to be female, were more often unmarried or living alone, and had a lower level of education compared to their pre-frail and non-frail counterparts. The difference between the scores in the social, psychological and physical domains were statistically significant between the three frailty stages. The most preferable scores came from the non-frail group, and least preferable scores were from the frail group. For example use of informal care: non-frail 3.9 %, pre-frail 23.8 %, frail 60.6 %, and GARS IADL-disability mean scores: non-frail 9.2, pre-frail 13.0, frail 19.7. Conclusion: When older people were categorised according to the three frailty stages, as described by Fried and colleagues, there were statistically significant differences in the level of social, psychological and physical functioning between the non-frail, pre-frail and frail persons. Non-frail participants had consistently more preferable scores compared to the frail participants. This indicated that the Fried frailty criteria could help healthcare professionals identify and treat frail older people in an efficient way, and provide indications for problems in other domains.
Frailty in older adults is an increasing burden for public health, both globally as well as in The Netherlands. To focus on frailty prevention from a public health perspective, a clear understanding of frailty prevalence is needed.
Abstract Purpose: This study aimed to establish which determinants had an effect on frailty among acutely admitted patients, where frailty was identified at discharge. In particular, our study focused on associations of sex with frailty. Methods: A cross-sectional study was designed using a sample of 1267 people aged 65 years or older. The Tilburg Frailty Indicator (TFI), a user-friendly self-report questionnaire was used to measure multidimensional frailty (physical, psychological, social) and determinants of frailty (sex, age, marital status, education, income, lifestyle, life events, multimorbidity). Results: The mean age of the participants was 76.8 years (SD 7.5; range 65-100). The bivariate regression analyses showed that all determinants were associated with total and physical frailty, and six determinants were associated with psychological and social frailty. Using multiple linear regression analyses, the explained variances differed from 3.5% (psychological frailty) to 20.1% (social frailty), with p values < 0.001. Of the independent variables age, income, lifestyle, life events, and multimorbidity were associated with three frailty variables, after controlling for all the other variables in the model. At the level of both frailty domains and components, females appeared to be more frail than men. Conclusion: The present study showed that sociodemographic characteristics (sex, age, marital status, education, income), lifestyle, life events, and multimorbidity had a different effect on total frailty and its domains (physical, psychological, social) in a sample of acute admitted patients.
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Ouderen hebben bij een stijgende leeftijd een grotere kans op frailty (kwetsbaarheid), een toestand van verminderde reservecapaciteit die ontstaat door afname van fysieke, psychologische en sociale capaciteit. Een relatief kleine aandoening of gebeurtenis kan een sterke achteruitgang in functioneren en zorgafhankelijkheid veroorzaken, waardoor ernstige complicaties kunnen ontstaan, zoals valincidenten, ziekenhuisopname en vroegtijdig overlijden. Het is daarom van belang dat (toekomstige) zorgverleners vroegtijdig en adequaat ingrijpen om frailty te voorkomen/verminderen. Dit project is ingebed in het Centre of Expertise Healthy Ageing (speerpunt FRAILTY), het Lectoraat Healthy Ageing, Allied Health Care and Nursing (LAHC) en het SPRONG-onderzoeksprogramma FAITH, welke focust op frailty. Praktijkpartners maken structureel onderdeel uit van FAITH en van het lectoraat. Het onderzoek sluit aan bij bestaande innovatie-/kenniswerkplaatsen waarin onderwijs, onderzoek en praktijk al samenwerken. Op dit moment worden o.a. de behoeften van werkveldpartners geïnventariseerd door een student aan de hand van interviews. Er zijn veel instrumenten voorhanden om de frailty status van een cliënt te bepalen. Echter deze worden in de praktijk vaak niet gebruikt. De (toekomstige) professional beoordeelt frailty soms helemaal niet of alleen globaal op eigen oordeel. Het gevolg hiervan is dat de cliënt niet optimaal behandeld wordt met alle medische en economische (kosten) gevolgen van dien. Het doel van dit project is om: • Het professioneel handelen te versterken door het concept frailty toepasbaar te maken voor de zorgpraktijk en het zorgonderwijs • Toepasbare assessmenttools te ontwikkelen waarmee frailty beoordeeld kan worden en leidend kunnen zijn in de keuze voor interventies en dit te implementeren in het onderwijs • Te analyseren wat de kostenbesparing is voor de gezondheidszorg als de professional het bruikbare meetinstrument of set instrumenten tijdig en optimaal inzet vergeleken met de huidige situatie waarin dit niet gebeurt (zoals boven beschreven). Bedoeling is om de postdoc-positie na 2 jaar te continueren en structureel te maken.
De samenwerking tussen de onderzoeksgroep FRIA van de Vrije Universiteit Brussel, afdeling oudergeneeskunde van het UMCG Groningen en de onderzoeksgroep (lectoraat) Healthy Ageing, Allied health Care and Nursing van de Hanzehogeschool Groningen is gericht op onderzoek naar bewegingsstoornissen bij veroudering. In het bijzonder wordt gekeken naar paratonic, een bewegingsstoornis bij dementie.The International Joint Research group ‘Move in Age’ concluded in a systematic review that paratonia still is a barely understood and devastating phenomenon in dementia and revealed the urgency of gaining more insight in the pathophysiology. Paratonia, a distinctive change in muscle tone, starts in early stages of dementia and develops further with progress of the disease. Resulting in severe discomfort for patients, but also affecting caregivers since daily care becomes increasingly difficult. It is hypothesized that changes in motor control due to dementia influences peripheral neurological control and biomechanical muscle structures (by crosslinking and inflammation caused by advanced glycation end-products (AGEs).This IJRG started in 2018 and aims to develop a long-term comprehensive research program on movement-related impairments at higher age. The three partners have a strong track record on research in the area of movement-related impairments in older persons; however, each focusing on a specific aspect. In fact, the Frailty in Ageing research group (FRIA) of the Vrije Universiteit Brussel (VUB) is running focused research program on the triad sarcopenia-dynapenia-inflammation with mainly a bio-gerontological and bio-psycho-medical approach; the department of General Practice and Elderly Care Medicine of the University Medical Center Groningen (UMCG) has anongoing research line on the medical aspects of mobility impairments in frail elderly persons and in elderly dementia patients; and finally Research Group Healthy Ageing, Allied Health Care and Nursing of the Hanze University of Applied Sciences Groningen (HUAS) developed a research program on physical, psycho-cognitive and social dimensions of frailty including the functional impact of mobility impairments. In the first 3-5 years, the focus will be on the movement-related impairments that occur in patients with dementia and in specific on paranoia. The programme will be extended towards movement-related impairments in the context of other geriatric syndromes.
