Groente en fruit bevatten tal van belangrijke voedingsstoffen. Het belang van groente en fruit als onderdeel van een gezond voedingspatroon wordt telkens weer bevestigd in wetenschappelijke studies. Zo is er overtuigend bewijs dat verhogen van de groente- en fruitconsumptie leidt tot een lagere bloeddruk en een lager risico op hart- en vaatziekten en beroertes. Ook relaties met andere ziekten worden steeds meer gelegd. De consumptie van groente en fruit is bij de meeste mensen echter veel lager dan de norm. Sterker nog, de consumptie lijkt de afgelopen jaren zelfs te dalen. Dat is vreemd, gezien de stijgende belangstelling van consumenten voor gezonde voeding en de stijgende kosten voor de zorg. Wat is de reden voor deze lage consumptiecijfers en, nog interessanter, wat is daar aan te doen? Het lectoraat Groene Gezondheid stelt zich tot doel om kennis te ontwikkelen en te verspreiden rond voedingswaarde en de consumptie van groente en fruit, om daarmee bij te dragen aan een gezonder eetpatroon en een reductie van zorgkosten.
MULTIFILE
To treat microbial infections, antibiotics are life-saving but the increasing antimicrobial resistance is a World-wide problem. Therefore, there is a great need for novel antimicrobial substances. Fruit and flower anthocyanins have been recognized as promising alternatives to traditional antibiotics. How-ever, for future application as innovative alternative antibiotics, the full potential of anthocyanins should be further investigated. The antimicrobial potential of anthocyanin mixtures against different bacterial species has been demonstrated in literature. Preliminary experiments performed by our laboratories, using grape, rose and red cabbage anthocyanins against S. aureus and E. coli confirmed the antimicrobial potential of these substances. Hundreds of different anthocyanin entities have been described. However, which of these entities hold antimicrobial effects is currently unknown. Our preliminary data show that an-thocyanins extracted from grape, rose and red cabbage contain different collections of anthocyanin entities with differential antimicrobial efficacies. Our focus is on the extraction and characterization of anthocyanins from various crop residues. Grape peels are residues in the production of wine, while red rose and tulip leaves are residues in the production of tulip bulbs and regular horticulture. The presence of high-grade substances for pharmacological purposes in these crops may provide an innovative strategy to add value to other-wise invaluable crop residues. This project will be performed by the collaborative effort of our institute together with the Medi-cal Microbiology department of the University Medical Center Groningen (UMCG), 'Wijnstaete', a small-scale wine-producer (Lemelerveld) and Imenz Bioengineering (Groningen), a company that develops processes to improve the production of biobased chemicals from waste products. Within this project, we will focus on the antimicrobial efficacy of anthocyanin-mixtures from sources that are abundantly and locally available as a residual waste product. The project is part of a larger re-search effect to further characterize, modify and study the antimicrobial effects of specific anthocy-anin entities.
