Op het congres van de Britisch Transplant Society en de Nederlandse Transplantatie Vereniging dat gehouden werd in Bournemouth, Engeland is deze bijgevoegde poster gepresenteerd. De poster beschrijft het onderzoek naar de inspanningstolerantie van mensen na een orgaantransplantatie op grote hoogte, tijdens de beklimming van de Kilimanjaro.
BACKGROUND: It is generally unknown to what extent organ transplant recipients can be physically challenged. During an expedition to Mount Kilimanjaro, the tolerance for strenuous physical activity and high-altitude of organ transplant recipients after various types of transplantation was compared to non-transplanted controls.METHODS: Twelve organ transplant recipients were selected to participate (2 heart-, 2 lung-, 2 kidney-, 4 liver-, 1 allogeneic stem cell- and 1 small bowel-transplantation). Controls comprised the members of the medical team and accompanying family members (n = 14). During the climb, cardiopulmonary parameters and symptoms of acute mountain sickness were recorded twice daily. Capillary blood analyses were performed three times during the climb and once following return.RESULTS: Eleven of the transplant participants and all controls began the final ascent from 4700 meters and reached over 5000 meters. Eight transplant participants (73%) and thirteen controls (93%) reached the summit (5895m). Cardiopulmonary parameters and altitude sickness scores demonstrated no differences between transplant participants and controls. Signs of hyperventilation were more pronounced in transplant participants and adaptation to high-altitude was less effective, which was related to a decreased renal function. This resulted in reduced metabolic compensation.CONCLUSION: Overall, tolerance to strenuous physical activity and feasibility of a high-altitude expedition in carefully selected organ transplant recipients is comparable to non-transplanted controls.
The decomposition of a body is influenced by burial conditions, making it crucial to understand the impact of different conditions for accurate grave detection. Geophysical techniques using drones have gained popularity in locating clandestine graves, offering non-invasive methods for detecting surface and subsurface irregularities. Ground-penetrating radar (GPR) is an effective technology for identifying potential grave locations without disturbance. This research aimed to prototype a drone system integrating GPR to assist in grave localization and to develop software for data management. Initial experiments compared GPR with other technologies, demonstrating its valuable applicability. It is suitable for various decomposition stages and soil types, although certain soil compositions have limitations. The research used the DJI M600 Pro drone and a drone-based GPR system enhanced by the real-time kinematic (RTK) global positioning system (GPS) for precision and autonomy. Tests with simulated graves and cadavers validated the system’s performance, evaluating optimal altitude, speed, and obstacle avoidance techniques. Furthermore, global and local planning algorithms ensured efficient and obstacle-free flight paths. The results highlighted the potential of the drone-based GPR system in locating clandestine graves while minimizing disturbance, contributing to the development of effective tools for forensic investigations and crime scene analysis.
MULTIFILE
The utilization of drones in various industries, such as agriculture, infrastructure inspection, and surveillance, has significantly increased in recent years. However, navigating low-altitude environments poses a challenge due to potential collisions with “unseen” obstacles like power lines and poles, leading to safety concerns and equipment damage. Traditional obstacle avoidance systems often struggle with detecting thin and transparent obstacles, making them ill-suited for scenarios involving power lines, which are essential yet difficult to perceive visually. Together with partners that are active in logistics and safety and security domains, this project proposal aims at conducting feasibility study on advanced obstacle detection and avoidance system for low-flying drones. To that end, the main research question is, “How can AI-enabled, robust and module invisible obstacle avoidance technology can be developed for low-flying drones? During this feasibility study, cutting-edge sensor technologies, such as LiDAR, radar, camera and advanced machine learning algorithms will be investigated to what extent they can be used be to accurately detect “Not easily seen” obstacles in real-time. The successful conclusion of this project will lead to a bigger project that aims to contribute to the advancement of drone safety and operational capabilities in low-altitude environments, opening new possibilities for applications in industries where low-flying drones and obstacle avoidance are critical.
Het haalbaarheidsonderzoek HESCO (High-End-Solar-Composites) beoogd succesvolle integratie van zonnecellen in hoogwaardige composieten. Reguliere zonnepanelen zijn door gewicht slecht inzetbaar voor mobiele oplossingen. Dunne flexibele zonnepanelen zijn kwetsbaar en hebben een lage efficiency. HESCO heeft als doel een zonnepaneel te ontwikkelen voor toepassingen waar vorm, gewicht, energieopbrengst en levensduur belangrijk zijn. Integratie van zonnecellen in lichtgewicht composieten maakt het mogelijk om deze zonnepanelen te maken. Het Lectoraat Kunststoftechnologie van Windesheim en bedrijf Mito Solar bundelen kennis op gebied van composieten en zonne-energie voor deze nieuwe toepassing. HESCO wordt onderzocht door een zonne-energie vleugel te ontwikkelen voor de HALE-UAV drones (High-Altitude-Long-Endurance-Unmanned-AerialVehicle).
In the past decade, particularly smaller drones have started to claim their share of the sky due to their potential applications in the civil sector as flying-eyes, noses, and very recently as flying hands. Network partners from various application domains: safety, Agro, Energy & logistic are curious about the next leap in this field, namely, collaborative Sky-workers. Their main practical question is essentially: “Can multiple small drones transport a large object over a high altitude together in outdoor applications?” The industrial partners, together with Saxion and RUG, will conduct feasibility study to investigate if it is possible to develop these collaborative Sky-workers and to identify which possibilities this new technology will offer. Design science research methodology, which focuses on solution-oriented applied research involving multiple iterations with rigorous evaluations, will be used to research the feasibility of the main technological building blocks. They are: • Accurate localization based on onboard sensors. • Safe and optimal interaction controller for collaborative aerial transport Within this project, the first proof-of-concepts will be developed. The results of this project will be used to expand the existing network and formulate a bigger project to address additional critical aspects in order to develop a complete framework for collaborative drones.
