This study explores the psychometric qualities of the Relevance of History Measurement Scale (RHMS), a questionnaire designed to measure students’ beliefs about the relevance of history. Participants were 1459 Dutch secondary school students aged between 12 and 18. Data analysis revealed three reliable factors, compliant with our theoretical framework which defines three strands of relevance of history: relevance for building a personal identity, for citizenship, and for insight into ‘the human condition’. The convergent and known-groups validity of the RHMS was demonstrated. The collected data show that students find history more relevant as they grow older, with most progress taking place between 14 and 16. Out of the three strands of relevance, building a personal identity scores lowest in students’ appraisals. This study shows that the RHMS is psychometrically sound and can be used to evaluate effects of lesson interventions directed at enhancing the relevance of history to students.
Using the past to orientate on the present and the future can be seen as one of history’s main contributions to educating future citizens of democratic societies. This thesis defines and explores aims and methods that may support teachers and students in making meaningful connections between the past, the present and the future in history class. Measurements with the Relevance of History Measurement Scale (RHMS), which was specifically developed for the purpose of this thesis, revealed that this type of history teaching positively affects students’ views on the relevance of history. This is an important outcome, because young students in particular have difficulty seeing the benefits of studying the past. Enabling them to see the relevance of history may be an important means to stimulate their motivation and engagement, because students’ appreciation of the value of school subjects is key to their commitment in school work.
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Competencies deemed relevant and meaningful by international business professionals and implemented in IB education still do not produce work-ready graduates. This may be because these competencies are not perceived as relevant or meaningful by students. This study was conducted to gain students’ perspectives on the relevance and meaningfulness of the HTIBP talent competency framework and how they perceived working with it. Results show that the five competency domains of the HTIBP competency framework are perceived as relevant and meaningful by students, in alignment with the professional field, however, this was not the case for a few associated items (behaviors) like “showing entrepreneurship” and “improving ideas from others.” The lack of clarity of these behaviors resulted in less experienced relevance and meaningfulness by students. Our findings will help educators to better facilitate students’ understanding the meaning and relevance of competencies. This may help to improve alignment with the professional field.
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Developing a framework that integrates Advanced Language Models into the qualitative research process.Qualitative research, vital for understanding complex phenomena, is often limited by labour-intensive data collection, transcription, and analysis processes. This hinders scalability, accessibility, and efficiency in both academic and industry contexts. As a result, insights are often delayed or incomplete, impacting decision-making, policy development, and innovation. The lack of tools to enhance accuracy and reduce human error exacerbates these challenges, particularly for projects requiring large datasets or quick iterations. Addressing these inefficiencies through AI-driven solutions like AIDA can empower researchers, enhance outcomes, and make qualitative research more inclusive, impactful, and efficient.The AIDA project enhances qualitative research by integrating AI technologies to streamline transcription, coding, and analysis processes. This innovation enables researchers to analyse larger datasets with greater efficiency and accuracy, providing faster and more comprehensive insights. By reducing manual effort and human error, AIDA empowers organisations to make informed decisions and implement evidence-based policies more effectively. Its scalability supports diverse societal and industry applications, from healthcare to market research, fostering innovation and addressing complex challenges. Ultimately, AIDA contributes to improving research quality, accessibility, and societal relevance, driving advancements across multiple sectors.
Mode heeft een cruciale functie in de samenleving: zij maakt diversiteit en inclusiviteit mogelijk en is een middel voor individuen om zich uit te drukken. Desalniettemin is mode ook een raadsel op het gebied van duurzaamheid, zowel aan de sociale als aan de milieukant. Er bestaan echter alternatieven voor de huidige praktijken in de mode. Dit project heeft tot doel de ontwikkeling van een van die initiatieven te ondersteunen. In samenwerking met twee Nederlandse MKB bedrijven in de mode-industrie, willen we een of meer business modellen co-designen voor het vermarkten van circulair ontworpen laser geprinte T-shirts. Door lasertechnologie te introduceren in plaats van traditionele inktopties, kunnen de T- shirts hun CO2 voetafdruk verder verkleinen en een verstandig alternatief zijn voor individuen, die op zoek zijn naar duurzame modekeuzes. Maar hoewel de technologische haalbaarheid vaststaat, vereist het vermarkten sterke, schaalbare, bedrijfsmodellen. Via een haalbaarheidsstudie willen we dergelijke businessmodellen ontwikkelen en de commercialisering van deze producten ondersteunen. Wij zijn van plan de reacties van de consument op een dergelijke innovatie te bestuderen, evenals de belemmeringen en stimulansen vanuit het oogpunt van de consument, en de inkoop-, toeleveringsketen- en financiële kwesties die kunnen voortvloeien uit de schaalbaarheid van een potentieel bedrijfsmodel. Om praktische relevantie voor de bredere industrie te verzekeren, streven we ernaar om de resultaten te presenteren op evenementen georganiseerd door een van de consortiumpartners (in 2023), als ook om een teaching case en een wetenschappelijk artikel te ontwikkelen op basis van de resultaten van het project.
Chemo-enzymatic peptide synthesis is unique in enabling the fast and sustainable synthesis of cyclic peptides, complex peptides and functionalized mini-proteins. The starting materials are routinely obtained by solid-phase peptide synthesis. One of the starting materials requires an oxo-ester functionality for recognition by the enzymes active site. The SPPS-based synthesis of the oxo-ester functionality still suffers from significant byproduct formation and low overall synthesis yields. The solution to this is introduction of the oxo-ester functionality at the end of the SPPS via a so-called Passerini reaction. Such a process does not only result in a more efficient production of cyclic or long peptides, but also expand the scope towards proteins derived from biological synthesis (i.e. recombinant proteins). To highlight the relevance of this proposed methodology, we will demonstrate a site-selective modification of the pharmaceutically important drug insulin.
