Zoekresultaten

Simulation-based virtual cycle for multi-level airport analysis

The aeronautical industry is expanding after a period of economic turmoil. For this reason, a growing number of airports are facing capacity problems that can sometimes only be resolved by expanding infrastructure, with the inherent risks that such decisions create. In order to deal with uncertainty at different levels, it is necessary to have relevant tools during an expansion project or during the planning phases of new infrastructure. This article presents a methodology that combines simulation approaches with different description levels that complement each other when applied to the development of a new airport. The methodology is illustrated with an example that uses two models for an expansion project of an airport in The Netherlands. One model focuses on the operation of the airport from a high-level position, while the second focuses on other technical aspects of the operation that challenge the feasibility of the proposed configuration of the apron. The results show that by applying the methodology, analytical power is enhanced and the risk of making the wrong decisions is reduced. We identified the limitations that the future facility will have and the impact of the physical characteristics of the traffic that will operate in the airport. The methodology can be used for tackling different problems and studying particular performance indicators to help decision-makers take more informed decisions.

The cerebral organization of audiomotor transformations in music

The realization of one’s musical ideas at the keyboard is dependent on the ability to transform sound into movement, a process called audiomotor transformation. Using fMRI, we investigated cerebral activations while classically-trained improvising and non-improvising musicians imagined playing along with recordings of familiar and unfamiliar music excerpts. We hypothesized that audiomotor transformation would be associated with the recruitment of dedicated cerebral networks, facilitating aurally-cued performance. Results indicate that while all classically-trained musicians engage a left-hemisphere network involved in motor skill and action recognition, only improvising musicians additionally recruit a right dorsal frontoparietal network dedicated to spatially-driven motor control. Mobilization of this network, which plays a crucial role in the real-time transformation of imagined or perceived music into goal-directed action, may be held responsible not only for the stronger activation of auditory cortex we observed in improvising musicians in response to the aural perception of music, but also for the superior ability to play ‘by ear’ which they demonstrated in a follow-up study. The results of this study suggest that the practice of improvisation promotes the implicit acquisition of hierarchical music syntax which is then recruited in top-down manner via the dorsal stream during music performance. In a study of audiomotor transformation in Parkinson patients, we demonstrated a dissociation between dysprosody in speech and music. While patients’ speech could reliably be distinguished from that of healthy individuals, purely on the basis of aural perception, no difference was observed between patients and healthy controls in their ability to sing improvised melodies.

Sustainability of urban freight transport

Crossing boundaries

The aim of the present thesis was to contribute to the improvement of patient care communication across the integrated care setting of children with cerebral palsy. Hereto, we followed two subsequent phases: 1) obtaining a better understanding of the experienced quality of patient care communication across the integrated care setting of cerebral palsy in three Dutch care regions; and 2) investigating the feasibility and usability of an eHealth application to improve patient care communication in these care regions.