Background: It is thought that physical health conditions start at a young age in people with profound intellectual and multiple disabilities (PIMD). Knowledge regarding the prevalence, associations and development of these physical health conditions could be used for purposes of prevention as well as appropriate care and support but is currently lacking. Objective: The aim of this study is to gain insight into the prevalence of physical health conditions and associations between these conditions in young children with PIMD. Methods: The study used cross-sectional data related to the physical health conditions of children with PIMD (n = 51, aged between 12 and 61 months). Data were collected in Belgium and in the Netherlands through a checklist filled in by primary caregiver(s). Physical health conditions were classified into categories by the 10th revision of the International Classification of Diseases and Related Health Problems (ICD-10) system. The number of physical health conditions and associations between them were analysed. The analysis focused on prevalence rates and associations represented by odds ratios (p < 0.05). A graphical model was estimated to represent dependencies and conditional dependencies between physical health conditions. Results: We found a mean of 3.8 (range 1–8, SD 1.9) physical health conditions per child. Most of the physical health conditions were found in the ICD-10 chapter ‘Nervous System’, with hypotonia as the most frequent at 70.6%. Five significant large associations were found between spasticity–contractures (OR 9.54); circulatory system–contractures (OR 7.50); scoliosis–contractures (OR 10.25); hearing impairments–skin problems (OR 58.20) and obstipation–hypotonia (OR 19.98). Conclusion: This study shows that at a young age, multiple physical health conditions are present in children with PIMD. In addition, we found five associations between physical health conditions.
Light enables us to see and perceive our environment but it also initiates effects beyond vision, such as alertness. Literature describes that at least six factors are relevant for initiating effects beyond vision. The exact relationship between these factors and alertness is not yet fully understood. In the current field study, personal lighting conditions of 62 Dutch office workers (aged 49.7 ± 11.4 years) were continuously measured and simultaneously self-reported activities and locations during the day were gathered via diaries. Each office worker participated 10 working days in spring 2017. Personal lighting conditions were interpreted based on four of the six factors (light quantity, spectrum, timing, and duration of light exposure). Large individual differences were found for the daily luminous exposures, illuminances, correlated colour temperatures, and irradiances measured with the blue sensor area of the dosimeter. The average illuminance (over all participants and all days) over the course of the day peaked three times. The analysis of the duration of light exposure demonstrated that the participants were on average only exposed to an illuminance above 1000 lx for 72 minutes per day. The interpretation of personal lighting conditions based on the four factors provides essential information since all of these factors may be relevant for initiating effects beyond vision. The findings in the current paper give first in-depth insight in the possibilities to interpret personal lighting conditions of office workers.
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Journal of Physics: Conference Series Paper • The following article is Open access Exploring the relationship between light and subjective alertness using personal lighting conditions J. van Duijnhoven1, M.P.J. Aarts1, E.R. van den Heuvel2 and H.S.M. Kort3,4 Published under licence by IOP Publishing Ltd Journal of Physics: Conference Series, Volume 2042, CISBAT 2021 Carbon-neutral cities - energy efficiency and renewables in the digital era 8-10 September 2021, EPFL Lausanne, Switzerland Citation J. van Duijnhoven et al 2021 J. Phys.: Conf. Ser. 2042 012119 Download Article PDF References Download PDF 29 Total downloads Turn on MathJax Share this article Share this content via email Share on Facebook (opens new window) Share on Twitter (opens new window) Share on Mendeley (opens new window) Hide article information Author e-mails j.v.duijnhoven1@tue.nl Author affiliations 1 Building Lighting Group, Department of the Built Environment, Eindhoven University of Technology, Eindhoven, The Netherlands 2 Stochastics, Department of Mathematics and Computer Science, Eindhoven University of Technology, Eindhoven, The Netherlands 3 Research Centre Healthy and Sustainable Living, University of Applied Sciences Utrecht, Utrecht, The Netherlands 4 Building Healthy Environments for Future Users Group, Department of the Built Environment, Eindhoven University of Technology, Eindhoven, The Netherlands DOI https://doi.org/10.1088/1742-6596/2042/1/012119 Buy this article in print Journal RSS Sign up for new issue notifications Create citation alert Abstract The discovery of the ipRGCs was thought to fully explain the mechanism behind the relationship between light and effects beyond vision such as alertness. However, this relationship turned out to be more complicated. The current paper describes, by using personal lighting conditions in a field study, further exploration of the relationship between light and subjective alertness during daytime. Findings show that this relationship is highly dependent on the individual. Although nearly all dose-response curves between personal lighting conditions and subjective alertness determined in this study turned out to be not significant, the results may be of high importance in the exploration of the exact relationship.
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Chemical preservation is an important process that prevents foods, personal care products, woods and household products, such as paints and coatings, from undesirable change or decomposition by microbial growth. To date, many different chemical preservatives are commercially available, but they are also associated with health threats and severe negative environmental impact. The demand for novel, safe, and green chemical preservatives is growing, and this process is further accelerated by the European Green Deal. It is expected that by the year of 2050 (or even as soon as 2035), all preservatives that do not meet the ‘safe-by-design’ and ‘biodegradability’ criteria are banned from production and use. To meet these European goals, there is a large need for the development of green, circular, and bio-degradable antimicrobial compounds that can serve as alternatives for the currently available biocidals/ preservatives. Anthocyanins, derived from fruits and flowers, meet these sustainability goals. Furthermore, preliminary research at the Hanze University of Applied Science has confirmed the antimicrobial efficacy of rose and tulip anthocyanin extracts against an array of microbial species. Therefore, these molecules have the potential to serve as novel, sustainable chemical preservatives. In the current project we develop a strategy consisting of fractionation and state-of-the-art characterization methods of individual anthocyanins and subsequent in vitro screening to identify anthocyanin-molecules with potent antimicrobial efficacy for application in paints, coatings and other products. To our knowledge this is the first attempt that combines in-depth chemical characterization of individual anthocyanins in relation to their antimicrobial efficacy. Once developed, this strategy will allow us to single out anthocyanin molecules with antimicrobial properties and give us insight in structure-activity relations of individual anthocyanins. Our approach is the first step towards the development of anthocyanin molecules as novel, circular and biodegradable non-toxic plant-based preservatives.
Worldwide, coral reefs are rapidly declining due to increased sea water temperatures and other environmental stresses (Figure 1). To counter the extinction of major coral reef building species on the island of Bonaire, the non-profit organization Reef Renewal Foundation Bonaire is restoring degraded reef sites using corals that are grown in local nurseries. In these nurseries, corals are propagated on artificial trees using fragmentation. After 6-8 months of growth in the nursery, the corals are transplanted to degraded reef sites around the island. Over the years more than 21.000 corals have been outplanted to reef restoration sites in this way. These corals show high survivorship under natural reef conditions but remain under threat by environmental disturbances, such as increased water temperatures, diseases, and competition with macroalgae. A promising intervention to increase reef persistence and resilience is to manipulate the coral-associated microbiome. At present, the composition of the microbiome in nursery-reared and outplanted corals on Bonaire is unknown. The aim of the current project is to identify and isolate naturally occurring beneficial bacteria that may stimulate the resilience of these corals. Our key objectives are: 1) to assess the presence of functionally beneficial bacteria in corals in nursery and restoration sites on Bonaire using metagenomic screening. 2) to design culture strategies to isolate these functionally beneficial bacteria. In the future, a selection of these beneficial bacteria can be applied to the corals to increase their resilience against environmental disturbances.
Due to the existing pressure for a more rational use of the water, many public managers and industries have to re-think/adapt their processes towards a more circular approach. Such pressure is even more critical in the Rio Doce region, Minas Gerais, due to the large environmental accident occurred in 2015. Cenibra (pulp mill) is an example of such industries due to the fact that it is situated in the river basin and that it has a water demanding process. The current proposal is meant as an academic and engineering study to propose possible solutions to decrease the total water consumption of the mill and, thus, decrease the total stress on the Rio Doce basin. The work will be divided in three working packages, namely: (i) evaluation (modelling) of the mill process and water balance (ii) application and operation of a pilot scale wastewater treatment plant (iii) analysis of the impacts caused by the improvement of the process. The second work package will also be conducted (in parallel) with a lab scale setup in The Netherlands to allow fast adjustments and broaden evaluation of the setup/process performance. The actions will focus on reducing the mill total water consumption in 20%.
